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Continuous Process for Producing High Quality Anhydrosugar Alcohols
Process know-how for producing commercial quantities of very high quality mono and di-anhydrosugar alcohols is the essence of this technology. Key enhancements versus other synthesis methods are 1. Early separation of the desired product from undesirable byproducts by differential solution in a solvent, separation of the product from the solvent, and recycle of the solvent.2. Careful choice of solvent with appropriate product solubility AND ability to azeotrope with water for removal of the water of reaction from the reaction vessel,3. Consistent and reliable reaction conditions control, avoiding many side reactions. This technology enables viable, large-scale production in readily available equipment, creating anhydrosugar alcohols suitable for polymerizations and pharmaceutical end uses. Preferred starting materials include arabinitol, ribitol, D-glucitol (also known as D-sorbitol or sorbitol), D-mannitol (mannitol), galactitol and iditolCurrent production anhydrosugar alcohols discontinuous batch contaminated molecular weight byproduct Synthesis difficult temperature creates undesirable colored byproducts reaction rates slow practice operating range narrow

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