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| The present technology proposes a tricalcium-phosphate-based prosthetic material, which is a sintered ceramic body mainly consisting of tricalcium phosphate containing a limited amount of zinc. By virtue of the limited content of zinc and the form of solid solution in which zinc is contained, the material of the present technology exhibits an osteogenesis-promoting effect without toxicity, which is suitable as a surgical implant for a hard-tissue of a living body. .zinc-doped-tricalcium-phosphate-based ceramic material powder conventional known preparation materials solid-phase reaction liquid-phase mechanochemical starting compounds ions preferably view good sintering behavior the precipitates conducting solutions capable blending admixed soluble calculated amount content dopant together effect co-precipitation collected filtration followed drying calcination blended binder shaped green body subjected temperature sintered serve surgical implant hard-tissue combination alkoxide eg ethoxide phosphoric acid suspension hydroxide nitrate ammonium carbonate though limitative Zinc introduced carboxylates acetate lactate The calculation mixture 00126 126% weight 006 070% dried 40 150degree 60 100degree calcined treatment zinc-containing advantageous compression-molded compact Polyvinyl alcohols cases retained performed range 900 1200degree 1050 less 00126% sustained release toxicity against living possibly due excessively large released mentioned upper times average human bone Namely reported bones 00200% order pharmaceutical effects expected ingredient prosthetic substitute releasability concentration larger natural |
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