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| Minimally modified proteins have the potential to be extremely useful in pharmacological, cosmetic, food, and industrial products and processes due to highly evolved specificity and functionality. However, their utility is often diminished by inherent or pharmacokinetic instability and by the potential to cause harmful immune responses. Avatar's targeted DT-molecular stapling™ is fundamentally different from other approaches taken to resolve these issues, and promises to optimize the use of proteins that are presently underutilized, refractory to development or unprotected by robust IP.Structural stabilization prevents aggregate formation (preventing immune responses biologics) inhibits proteolytic degradation renal clearance lead longer periods exposure vivo |
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