Welcome
The yet2.com global technology marketplace lists intellectual property, technology, and patents for technology transfer, technology licensing, patent licensing and patent sale. As premier technology brokers, yet2.com offers this essential IP marketplace for technology owners, technology seekers, and technology brokers interested in technology acquisition, patent licensing, intellectual property licensing (IP licensing), and intellectual property transfer.   more...

 Interested?
This is an abstract of a technology that is available for sale or license. yet2.com can introduce you confidentially to the owner of this technology.
To view the complete TechPak, please register with us.

 Still looking?
Enter a keyword or phrase below, and search now to find other technologies of interest.
 
 TechPak Categories
Enzymatically-Produced Oligodendrocyte Cytotoxic Dimeric IL-2 Factor
Adult nerves of the mammalian central nervous system (CNS) show poor regenerative ability after axonal injury. The failure to regenerate has been attributed to the inhospitable nature of the nerve's environmental milieu, including the formation of mature oligodendrocytes which inhibit axonal growth. Interleukin-2 (IL-2), a lymphokine synthesized and secreted by T cells after activation, is upregulated in the brain following brain injury. This invention described a human dimeric IL-2 produced by enzymatic activity of nerve-derived transglutaminase which is selectively toxic to oligodendrocytes. No safe effective means for causing regenerative growth of CNS axons in mammals has yet been developed. A pharmaceutical which can be injected at the site of desired regeneration may help alleviate post-traumatic paraplegia or quadriplegia, blindness, deafness, surgically associated axotomy, etc.novel compound dimeric interleukin-2 (IL-2) derived incubation nerve-derived transglutaminase pharmaceutical mean induce facilitate regeneration

Interested? This is an abstract of a technology that is available for sale or license. yet2.com can introduce you confidentially to the owner of this technology.
To view the complete TechPak, please register with us.
yet2.com TechPakTM produced by yet2.com. For an introduction to the owner of this technology please visit www.yet2.com or call:
Boston, MA, USA
+1 (781) 972-0600
fax +1 (781) 972-0601
Liverpool, United Kingdom
+44 (0) 151 705 3539
fax +44 (0) 151 705 3542
Tokyo, Japan
+81-3-5217-0217
fax +81-3-5217-0218
Copyright © 1999-2008 by yet2.com, Inc. All Rights Reserved.