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Model will be developed in house and sublicensed when it is commercially applicable. The timeframe to perform the assay is less important than it's correlation to relevant in vivo models. ADMET screening; drug modeling; drug-drug interactions; renal transporters; renal clearance; renal excretion create novel ADMET looking assay predict model renal clearance cell-based fluorescence-based amenable 6-well plate minimum Ideally modified multiple species just models human excretion/clearance OK |
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