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An accurate, inexpensive, and fast test applicable on a large scale to a food production line. Consumer snack foods. Overview large global food company seeks rapid inexpensive reliable test detect even small levels acrylamide foods Background multi-national looking analyzing fried snack current industry/government accepted based LC/MS/MS (high performance liquid chromatography/tandem mass spectrometry) accurate reproducible sensitive selective 6-8 hours conduct Tedious sample preparation 2-3 hrs2 Expensive laboratory instruments >$300 K3 trained expert chemical analysts chromatography/mass equivalent data own particular issues points Constraints simple performed essentially on-line plant environment operators quality assurance Ideally little results less quantitative potato chip Specifically Sensitivity LOQ (limit quantitation) least 200 ppb ideally down 100 Ranges 1200 typical sampleso Reproducibility RSD (relative standard deviation) below 10% equal better higher levelso Accuracy Spike recovery ~90% ~110% good Selectivity No significant interferents matrix Solution Areas Research artificial sensingo Molecular biologyo Neural computingo Physics materials |
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