{"id":16230,"date":"2026-04-27T12:19:02","date_gmt":"2026-04-27T16:19:02","guid":{"rendered":"https:\/\/www.yet2.com\/active-projects\/%e6%b1%82%e3%82%81%e3%82%8b%e3%82%82%e3%81%ae%ef%bc%9a-%e8%87%a8%e5%ba%8a%e8%bb%a2%e5%b8%b0%e3%81%ae%e3%83%aa%e3%82%b9%e3%82%af%e3%82%92%e8%bb%bd%e6%b8%9b%e3%81%97%e3%80%81otc%ef%bc%8f%e5%8c%bb\/"},"modified":"2026-04-27T12:19:02","modified_gmt":"2026-04-27T16:19:02","slug":"seeking-human-pk-performance-modelling-and-translational-solutions-to-de-risk-clinical-outcomes-and-support-otc-pharmaceutical-development","status":"publish","type":"project","link":"https:\/\/www.yet2.com\/jp\/active-projects\/seeking-human-pk-performance-modelling-and-translational-solutions-to-de-risk-clinical-outcomes-and-support-otc-pharmaceutical-development\/","title":{"rendered":"\u6c42\u3081\u308b\u3082\u306e\uff1a 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https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?resize=1024%2C559&amp;quality=80&amp;ssl=1 1024w, https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?resize=768%2C419&amp;quality=80&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?resize=1536%2C838&amp;quality=80&amp;ssl=1 1536w, https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?resize=2048%2C1117&amp;quality=80&amp;ssl=1 2048w, https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?w=1600&amp;quality=80&amp;ssl=1 1600w, https:\/\/i0.wp.com\/www.yet2.com\/wp-content\/uploads\/Gemini_Generated_Image_h3ld5bh3ld5bh3ld-scaled.png?w=2400&amp;quality=80&amp;ssl=1 2400w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/h1>\n<p>&nbsp;<\/p>\n<h2> <\/h2>\n<p><strong>\u6982\u8981<\/strong><\/p>\n<p>\u3053\u306e\u6d88\u8cbb\u8005\u5411\u3051\u30d8\u30eb\u30b9\u30b1\u30a2\u4f01\u696d\u306f\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u5bfe\u3059\u308b\u4fe1\u983c\u6027\u3092\u5f37\u5316\u3057\u3001in-vitro\u304b\u3089\u81e8\u5e8a\u958b\u767a\u3078\u306e\u79fb\u884c\u3092\u6539\u5584\u3059\u308b\u305f\u3081\u306b\u3001\u8eab\u4f53\u304c\u6642\u9593\u3068\u3068\u3082\u306b\u85ac\u7269\u3068\u3069\u306e\u3088\u3046\u306b\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u304b\u3001\u3059\u306a\u308f\u3061PK\uff08\u85ac\u7269\u52d5\u614b\uff09\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3068\u6709\u52b9\u6027\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3092\u3088\u308a\u826f\u304f\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3059\u308b\u305f\u3081\u306e\u65b0\u3057\u3044\u30e2\u30c7\u30ea\u30f3\u30b0\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u3092\u6c42\u3081\u3066\u3044\u308b\u3002<\/p>\n<p><strong> <\/strong><\/p>\n<p><strong>\u80cc\u666f<\/strong><\/p>\n<p>\u4e00\u822c\u7528\u533b\u85ac\u54c1\uff08OTC\uff09\u306e\u65b0\u898f\u958b\u767a\u3084\u65e2\u5b58\u88fd\u5264\u306e\u5909\u66f4\u306f\u3001\u6642\u9593\u3068\u30b3\u30b9\u30c8\u306e\u304b\u304b\u308b\u30d7\u30ed\u30bb\u30b9\u3067\u3042\u308a\u3001\u5927\u898f\u6a21\u306aPK\u8a66\u9a13\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002\u3053\u306e\u7d44\u7e54\u3067\u306f\u3001PBPK\uff08\u751f\u7406\u5b66\u7684\u85ac\u7269\u52d5\u614b\u5b66\uff09\u30e2\u30c7\u30ea\u30f3\u30b0\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3001PKPD\uff08\u85ac\u7269\u52d5\u614b\u85ac\u529b\u5b66\uff09\u3001MPS\uff08\u5fae\u5c0f\u751f\u7406\u5b66\u7684\u30b7\u30b9\u30c6\u30e0\uff09\u3001\u305d\u306e\u4ed6\u306e\u65b0\u3057\u3044AI\/ML\u6280\u8853\u3092\u6d3b\u7528\u3057\u305f\u65b0\u3057\u3044\u30e2\u30c7\u30ea\u30f3\u30b0\u30a2\u30d7\u30ed\u30fc\u30c1\u306a\u3069\u3001PK\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u4e88\u6e2c\u3068\u81e8\u5e8a\u30ea\u30b9\u30af\u306e\u8efd\u6e1b\u3092\u53ef\u80fd\u306b\u3059\u308b\u69d8\u3005\u306a\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u30e2\u30c7\u30eb\u306e\u63a2\u6c42\u306b\u95a2\u5fc3\u304c\u3042\u308a\u307e\u3059\u3002 <\/p>\n<p>\u30e2\u30c7\u30eb\u306b\u306f\u3001in vitro\u30c7\u30fc\u30bf\u3068\u81e8\u5e8a\u7684\u610f\u7fa9\u53ca\u3073\u81e8\u5e8a\u7684\u6709\u52b9\u6027\uff08IVIVC\uff09\u3068\u306e\u76f8\u95a2\u304c\u3042\u308a\u3001\u69d8\u3005\u306a\u96c6\u56e3\uff08\u4f8b\uff1a\u5c0f\u5150\u3001\u9ad8\u9f62\u8005\u3001\u598a\u5a66\u3001\u81d3\u5668\u969c\u5bb3\u3001\u305d\u306e\u4ed6\u306e\u751f\u7406\u5b66\u7684\u8981\u56e0\u306e\u5909\u5316\uff09\u306b\u304a\u3051\u308b\u85ac\u7269PK\u3092\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\uff0f\u4e88\u6e2c\u3059\u308b\u80fd\u529b\u304c\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3002\u5065\u5e38\u60a3\u8005\u306b\u304a\u3051\u308b\u30e2\u30c7\u30ea\u30f3\u30b0\u3082\u6709\u76ca\u3067\u3042\u308d\u3046\u3002 <\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u4e3b\u8981\u57fa\u6e96<\/strong><\/p>\n<p><strong>\u5fc5\u9808<\/strong><\/p>\n<ul>\n<li>\u898f\u5236\u5f53\u5c40\u306e\u671f\u5f85\uff08\u4f8b\uff1aFDA\u3001MHRA\uff09\u3092\u6e80\u305f\u3059\u7cbe\u5ea6\u3067PK\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u4e88\u6e2c\u3059\u308b\u5b9f\u8a3c\u3055\u308c\u305f\u80fd\u529b<\/li>\n<li>\u898f\u5236\u5f53\u5c40\u306e\u53d7\u5bb9\u6027\u304c\u5b9f\u8a3c\u3055\u308c\u305f\u78ba\u7acb\u3055\u308c\u305fIVIVC\uff08\u4f8b\uff1aFDA\u30ec\u30d9\u30ebA\/B\u76f8\u95a2\u57fa\u6e96\uff09<\/li>\n<\/ul>\n<p><strong>\u6301\u3063\u3066\u3044\u3066\u3088\u304b\u3063\u305f<\/strong><\/p>\n<ul>\n<li>\u30b3\u30f3\u30b7\u30e5\u30fc\u30de\u30fc\u30d8\u30eb\u30b9\u30b1\u30a2\u306e\u7d4c\u9a13<\/li>\n<li>\u7d4c\u53e3\u5f90\u653e\u88fd\u5264\u304a\u3088\u3073\u9045\u5ef6\u653e\u51fa\u88fd\u5264\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308bPBPK\u30e2\u30c7\u30ea\u30f3\u30b0<\/li>\n<li>\u7d4c\u9f3b\u304a\u3088\u3073\u5c40\u6240\u30c7\u30ea\u30d0\u30ea\u30fc\u306e\u30e2\u30c7\u30ea\u30f3\u30b0<\/li>\n<li>MHRA\u3001FDA\u3001\u305d\u306e\u4ed6\u540c\u7b49\u306e\u898f\u5236\u5f53\u5c40\u306b\u3088\u308b\u627f\u8a8d\u3002<\/li>\n<li>\u8cbb\u7528\u5bfe\u52b9\u679c<\/li>\n<\/ul>\n<p><strong> <\/strong><\/p>\n<p><strong>\u8003\u3048\u3089\u308c\u308b\u89e3\u6c7a\u7b56<\/strong><\/p>\n<p>\u3053\u306e\u30af\u30e9\u30a4\u30a2\u30f3\u30c8\u306f\u3001\u4ee5\u4e0b\u3092\u542b\u3080\u304c\u3053\u308c\u306b\u9650\u5b9a\u3055\u308c\u306a\u3044\u69d8\u3005\u306a\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u306b\u524d\u5411\u304d\u3067\u3042\u308b\uff1a<\/p>\n<ul>\n<li>\u751f\u7406\u5b66\u7684\u85ac\u7269\u52d5\u614b\u5b66\uff08PBPK\uff09\u30e2\u30c7\u30ea\u30f3\u30b0<\/li>\n<li>\u85ac\u7269\u52d5\u614b\u5b66\u7684\u85ac\u529b\u5b66\u7684\uff08PK\/PD\uff09\u30e2\u30c7\u30ea\u30f3\u30b0<\/li>\n<li>\u751f\u7406\u5b66\u7684\u751f\u7269\u85ac\u5264\u5b66\uff08PBBM\uff09\u30e2\u30c7\u30ea\u30f3\u30b0<\/li>\n<li>PBPK\u3068PKPD\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30e2\u30c7\u30eb\u60c5\u5831\u533b\u85ac\u54c1\u958b\u767a\uff08MIDD\uff09<\/li>\n<li>AL\/ML\u30a2\u30d7\u30ed\u30fc\u30c1<\/li>\n<li>PopPK &#8211; \u4eba\u53e3PK<\/li>\n<li>\u30c1\u30c3\u30d7\u4e0a\u306e\u81d3\u5668<\/li>\n<li>\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u30fb\u30a6\u30a7\u30c3\u30c8\u30fb\u30c9\u30e9\u30a4\u30fb\u30a2\u30d7\u30ed\u30fc\u30c1<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>\u89e3\u6c7a\u7b56\u306e\u671b\u307e\u3057\u3044\u7d50\u679c\uff1a<\/strong><\/p>\n<p>\u5f37\u529b\u306a\u9867\u5ba2\u30b5\u30dd\u30fc\u30c8\u304c\u5229\u7528\u53ef\u80fd\u3067\u3042\u308c\u3070\u3001\u30e2\u30c7\u30ea\u30f3\u30b0\u4f5c\u696d\u304a\u3088\u3073\/\u307e\u305f\u306f\u30bd\u30d5\u30c8\u30a6\u30a7\u30a2\u30e9\u30a4\u30bb\u30f3\u30b7\u30f3\u30b0\u3092\u8acb\u3051\u8ca0\u3046\u59d4\u8a17\u7814\u7a76\u6a5f\u95a2\u3092\u63a2\u3057\u3066\u3044\u308b\u3002  <\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u95a2\u9023\u30c6\u30c3\u30af\u30cb\u30fc\u30ba<\/strong><\/p>\n<p><a href=\"https:\/\/www.yet2.com\/jp\/active-projects\/csl-seeking-novel-approaches-for-digital-information-technology-innovation\/\" data-wpel-link=\"internal\">CSL 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[&hellip;]<\/p>\n","protected":false},"featured_media":16228,"menu_order":0,"template":"","specialties":[],"industry":[1945],"sector":[1943],"class_list":["post-16230","project","type-project","status-publish","has-post-thumbnail","hentry","industry-1945","sector-1943"],"_links":{"self":[{"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/project\/16230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/types\/project"}],"version-history":[{"count":0,"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/project\/16230\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/media\/16228"}],"wp:attachment":[{"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/media?parent=16230"}],"wp:term":[{"taxonomy":"specialties","embeddable":true,"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/specialties?post=16230"},{"taxonomy":"industry","embeddable":true,"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/industry?post=16230"},{"taxonomy":"sector","embeddable":true,"href":"https:\/\/www.yet2.com\/jp\/wp-json\/wp\/v2\/sector?post=16230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}