Welcome to CSL’s Open Innovation Submission Portal
CSL is a leading global biotech company that develops and delivers innovative biotherapies that help people with life-threatening medical conditions live full lives. Innovation has been in CSL’s DNA for more than a century. CSL has the full spectrum of strengths from research and clinical development to manufacturing and commercialization across six therapeutic areas of expertise. Their strengths enable them to accurately identify, successfully develop, and dependably deliver innovations for patients.
At CSL they believe that for innovation to be fast tracked, they need to partner with the brightest minds in the sector. They know that partnerships can accelerate innovation and delivery of new life-saving and protective medicines and they collaborate and work with external organizations that have unique technologies, assets and equipment, to address patients’ unmet needs around the globe.
If you have an idea related to new products, new technologies or new advancements relating to CSL’s areas of interest, please feel free to share it via the Submission Form. All submissions will be screened by yet2 and if successful, will be shared with CSL. Initial submissions should not include any confidential information.
Core interests for early stage partnering
CSL’s mission is to discover, develop and deliver our innovative therapies that improve the patients’ quality of life while maintaining the highest product safety standards and continually improving manufacturing effectiveness. We know that partnerships can accelerate innovation and delivery of new unique technologies, assets, and equipment, to address patients’ unmet needs around the globe. Below you will find our current interest areas where we seek innovative ideas that can improve our processes, equipment, and analytical capabilities within our three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapies.
Description
Separation of precipitated proteins from the protein solution without an advanced set up can cause direct loss of product, impacting protein recovery. There can be impact to product robustness and quality during the immediate separation step with potential consequences during the following purification processes. Additionally, these separations can require extensive cleaning of equipment.
Advanced set-ups can be achieved with better suited filter aids and filter media that reduce the loss of the target protein, which can have a large positive impact on product yield throughout the entire remaining purification and manufacturing process. Additionally, single use or easily cleanable filtration components can reduce turn-around time for the equipment as well as reduce energy and materials required for cleaning.
Background
Customer seeks to reduce product loss during solid: liquid separation of protein solutions. Targeted losses are for both the precipitate and filtrate.
Key Success Criteria
The solution must:
- Be applicable to plate and frame filter press set-up
- Meet regulatory and safety requirements for upstage pharmaceutical manufacturing
The client is interested in a measurable increase in product material, reducing equipment cleaning time, and improving sustainability.
Preferred Collaboration types
CSL and its affiliates are open to a range of collaboration types in this area.
Submit your solution here.
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