Overview:

Suntory Global Innovation Center, which is responsible for the basic research of the Suntory Group, is looking for a device (or technology) that can measure the absolute value of cerebral blood flow.

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Background:

At Suntory Global Innovation Center it is necessary to measure changes in blood flow when conducting long-term intervention tests on various ingredients related to dementia prevention etc. Magnetoencephalograph cannot measure blood flow.  As fNIRS can only obtain relative values, long-term blood flow improvement (change in blood flow after a long period of time) cannot be observed.  Since CT uses radioactive substances, it provides burden on human body. ASL can measure the absolute value of blood flow non-invasively, but there is a problem with accuracy.

Therefore, Suntory Global Innovation Center is looking for a device or technology that can measure the absolute value of the blood flow of the brain non-invasively and accurately.

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Constraints:

  • Ability to measure the absolute value of cerebral blood flow with high accuracy (reproducible)
  • (Changes in cerebral blood flow can be measured with long-term intervention)
  • Non-invasive
  • The actual machine is sold (or there is a prototype with which we can confirm it works.)
  • The technology can distinguish between signals of skin blood flow of scalp and that of cerebral blood flow.
  • Can be used for intervention test in Japan
  • It is better to measure blood flow at deeper part of the brain.
  • If there is no radiation exposure or non-invasive techniques, tracer can be used.
  • Technology that can measure amyloid β release from brain can also be considered

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Desired Timeframe:

Within 12 months

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Field of use and intended applications:

Medical equipment, pharmaceutical etc.

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Constraints:

  • Can be used for intervention test in Japan
  • It is better to measure blood flow at deeper part of the brain.
  • If there is no radiation exposure or non-invasive techniques, tracer can be used.
  • Technology that can measure amyloid β release from brain can also be considered

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Field of use and intended applications:

Intervention test