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Synthetic antioxidants such as Tinogard TT (Pentaerythrityl tetra-di-t-butly hydroxyhydrocinnamate) and Tinogard DA (didodecyl 3,3′-thiodipropionate) have been used as highly effective stabilizers to prevent degradation of actives sensitive to oxidation. They can mitigate negative impacts of oxidatively unstable actives on stability of final formulations. However, due to their synthetic nature, they are not suitable for use in natural Skin Care formulations. Some existing natural antioxidants such as tocopherol and rosemary extract come with strong odor or color profile, which introduced undesirable sensory attributes in final formulations. There is a need for natural alternative to TInogard TT and Tinogard DA antioxidants.


Natural antioxidant(s) for improving storage stability of fragrances and actives prone to oxidation. Natural antioxidant must be parity or superior in performance to Tinogard TT and Tinogard DA.

Desired Outcome

Proof of principle studies versus Tinogard TT and Tinogard DA:

  • GC headspace data after storage for benchmark actives: sunflower seed oil & CLA
  • Color and chemical stability data after storage
  • Rancimat test

What We Aren’t Interested In

  • Antioxidants with tox issue, registration issue, color issue or odor issue
  • Antioxidants that degrade during storage stability
  • Antioxidants that act as potent antioxidants in skin but have poor efficacy in preventing actives from oxidation during formulation storage stability

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